Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NP71 / MLXPL_HUMAN
Protein Name Carbohydrate-responsive element-binding protein
Gene Name Name: MLXIPL
Synonyms:BHLHD14,MIO,WBSCR14;
Organism Homo sapiens (Human)

PRO ID PR:Q9NP71
DAG View
PRO Name carbohydrate-responsive element-binding protein (human)
Definition A carbohydrate-responsive element-binding protein that is encoded in the genome of human.
Short Label hMLXIPL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NP71 (MLXIPL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation PhosphoSitePlus   UniProt 24275569
S23 Phosphorylation PhosphoSitePlus   UniProt 24275569
S25 Phosphorylation PhosphoSitePlus   UniProt 24275569
T27 Phosphorylation PhosphoSitePlus   UniProt 24275569
S29 Phosphorylation PhosphoSitePlus   UniProt 24275569
S33 Phosphorylation PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus   RLIMS-P 18606808, 22506051
T147 Phosphorylation PhosphoSitePlus
K171 Acetylation PhosphoSitePlus
S196 Phosphorylation P17612 (PRKACA) PRO   PhosphoSitePlus   RLIMS-P   UniProt 18606808, 23186163, 23918932, ...22506051
S499 Phosphorylation PhosphoSitePlus
S556 Phosphorylation PRO
S602 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S614 Phosphorylation PhosphoSitePlus   UniProt 23186163
S631 Phosphorylation PhosphoSitePlus   UniProt 24275569
T653 Phosphorylation PRO
T840 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S602 Phosphorylation HPRD 20166139
S614 Phosphorylation HPRD 20166139
T653 Phosphorylation HPRD 11698644
Site PTM Type PTM Enzyme Score Source PMID
S196 Phosphorylation HPRD 11698644
S602 Phosphorylation HPRD 20166139
S614 Phosphorylation HPRD 20166139
T653 Phosphorylation HPRD 11698644
Site PTM Type PTM Enzyme Score Source PMID
S196 Phosphorylation HPRD 11698644
S602 Phosphorylation HPRD 20166139
S614 Phosphorylation HPRD 20166139
T651 Phosphorylation HPRD 11698644
Site PTM Type PTM Enzyme Score Source PMID
S196 Phosphorylation HPRD 11698644
S602 Phosphorylation HPRD 20166139
S614 Phosphorylation HPRD 20166139
T651 Phosphorylation HPRD 11698644


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048385 (hMLXIPL/Phos:1) pS196,pT653 PRO
PR:000048386 (hMLXIPL/Phos:2) pS556 PRO
PR:000048387 (hMLXIPL/Phos:3) pT653 PRO


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9NP71 (MLXIPL) S196 O14980 (XPO1) unknown eFIP 18606808


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S29 L29 Biomuta DOID:1909 / melanoma [ cosmic ]
S140 N140 Biomuta DOID:1909 / melanoma [ icgc, tcga ]