iPTMnet Report for Q9HCR9 (PDE11A)
Protein Information
| UniProt AC / UniProt ID | Q9HCR9 / PDE11_HUMAN |
| Protein Name | Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A |
| Gene Name | Name: PDE11A |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9HCR9 |
| PRO Name | dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (human) |
| Definition | A dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A that is encoded in the genome of human. |
| Short Label | hPDE11A |
| Category | organism-gene |
DAG ViewQ9HCR9 (PDE11A) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S117 | Phosphorylation | P17612 (PRKACA) | score2 | PhosphoSitePlus | 18312413 | |
| T136 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S162 | Phosphorylation | P17612 (PRKACA) | score2 | PhosphoSitePlus | 18312413 | |
| S163 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S239 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
| T252 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S441 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S771 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S897 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T900 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S34 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S162 | R162 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S162 | G162 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S239 | P239 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S441 | F441 | Biomuta | [ cosmic ] | |
| S897 | L897 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
