iPTMnet Report for Q9HCR9 (PDE11A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCR9 / PDE11_HUMAN
Protein Name Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Gene Name Name: PDE11A
Organism Homo sapiens (Human)

PRO ID PR:Q9HCR9
DAG View
PRO Name dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (human)
Definition A dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A that is encoded in the genome of human.
Short Label hPDE11A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCR9 (PDE11A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S117 Phosphorylation PhosphoSitePlus 18312413
S117 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 18312413
T136 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus 18312413
S162 Phosphorylation P17612 (PRKACA) PhosphoSitePlus 18312413
S163 Phosphorylation PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus   UniProt 19690332
T252 Phosphorylation PhosphoSitePlus
S441 Phosphorylation PhosphoSitePlus
S771 Phosphorylation PhosphoSitePlus
S897 Phosphorylation PhosphoSitePlus
T900 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S31 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S162 R162 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S162 G162 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S239 P239 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S441 F441 Biomuta [ cosmic ]
S897 L897 Biomuta DOID:4159 / skin cancer [ cosmic ]