iPTMnet Report for Q9HCC9 (ZFYVE28)
Protein Information
| UniProt AC / UniProt ID | Q9HCC9 / LST2_HUMAN |
| Protein Name | Lateral signaling target protein 2 homolog |
| Gene Name | Name: ZFYVE28 Synonyms:KIAA1643,LST2; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9HCC9 |
| PRO Name | lateral signaling target protein 2 homolog (human) |
| Definition | A lateral signaling target protein 2 homolog that is encoded in the genome of human. |
| Short Label | hZFYVE28 |
| Category | organism-gene |
Q9HCC9 (ZFYVE28) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K87 | Ubiquitination | score3 | PhosphoSitePlus UniProt | 19460345 | ||
| Y239 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S334 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S392 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S394 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T516 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S586 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 19460345 | ||
| T870 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 19460345 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S334 | Y334 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
| T516 | M516 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T516 | S516 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View