Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HCC9 / LST2_HUMAN
Protein Name Lateral signaling target protein 2 homolog
Gene Name Name: ZFYVE28
Synonyms:KIAA1643,LST2;
Organism Homo sapiens (Human)

PRO ID PR:Q9HCC9
DAG View
PRO Name lateral signaling target protein 2 homolog (human)
Definition A lateral signaling target protein 2 homolog that is encoded in the genome of human.
Short Label hZFYVE28
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HCC9 (ZFYVE28) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K87 Ubiquitination PhosphoSitePlus   UniProt 19460345
Y239 Phosphorylation PhosphoSitePlus
S334 Phosphorylation PhosphoSitePlus   UniProt 23186163
S392 Phosphorylation PhosphoSitePlus
S394 Phosphorylation PhosphoSitePlus
T516 Phosphorylation PhosphoSitePlus   UniProt 23186163
S586 Phosphorylation PhosphoSitePlus   UniProt 19460345
T870 Phosphorylation PhosphoSitePlus   UniProt 19460345


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S334 Y334 Biomuta DOID:1319 / brain cancer [ icgc ]
T516 M516 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T516 S516 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]