iPTMnet Report for Q9HBG4 (ATP6V0A4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9HBG4 / VPP4_HUMAN
Protein Name V-type proton ATPase 116 kDa subunit a 4
Gene Name Name: ATP6V0A4
Synonyms:ATP6N1B,ATP6N2;
Organism Homo sapiens (Human)

PRO ID PR:Q9HBG4
DAG View
PRO Name V-type proton ATPase 116 kDa subunit a 4 (human)
Definition A V-type proton ATPase 116 kDa subunit a 4 that is encoded in the genome of human.
Short Label hATP6V0A4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9HBG4 (ATP6V0A4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K50 Ubiquitination PhosphoSitePlus
T87 Phosphorylation PhosphoSitePlus
T95 Phosphorylation HPRD   PhosphoSitePlus 20068231
K118 Ubiquitination PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
Y306 Phosphorylation PhosphoSitePlus
T333 Phosphorylation PhosphoSitePlus
T373 Phosphorylation PhosphoSitePlus
N489 N-Glycosylation GlyGen 27127844
S544 Phosphorylation PhosphoSitePlus
S688 Phosphorylation HPRD 20068231
S690 Phosphorylation HPRD 20068231
S692 Phosphorylation HPRD   phospho.ELM 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y306 N306 Biomuta DOID:1324 / lung cancer [ cosmic ]
N489 D489 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S544 L544 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S688 I688 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]