Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9HBG4 / VPP4_HUMAN
Protein Name V-type proton ATPase 116 kDa subunit a 4
Gene Name Name: ATP6V0A4
Organism Homo sapiens (Human)

DAG View
PRO Name V-type proton ATPase 116 kDa subunit a 4 (human)
Definition A V-type proton ATPase 116 kDa subunit a 4 that is encoded in the genome of human.
Short Label hATP6V0A4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9HBG4 (ATP6V0A4) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K50 Ubiquitination PhosphoSitePlus
T87 Phosphorylation PhosphoSitePlus
T95 Phosphorylation HPRD   PhosphoSitePlus 20068231
K118 Ubiquitination PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
Y306 Phosphorylation PhosphoSitePlus
T333 Phosphorylation PhosphoSitePlus
T373 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
S688 Phosphorylation HPRD 20068231
S690 Phosphorylation HPRD 20068231
S692 Phosphorylation HPRD   phospho.ELM 18669648

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S544 L544 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ icgc, tcga ]
S688 I688 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]