iPTMnet Report for Q9HA77 (CARS2)
Protein Information
UniProt AC / UniProt ID | Q9HA77 / SYCM_HUMAN |
Protein Name | Probable cysteine--tRNA ligase, mitochondrial precursor |
Gene Name | Name: CARS2 ORFNames:OK/SW-cl.10; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9HA77 |
PRO Name | probable cysteine--tRNA ligase, mitochondrial (human) |
Definition | A probable cysteine--tRNA ligase, mitochondrial that is encoded in the genome of human. |
Short Label | hCARS2 |
Category | organism-gene |
Q9HA77 (CARS2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T46 | Phosphorylation | score1 | PhosphoSitePlus | |||
S111 | Phosphorylation | score1 | PhosphoSitePlus | |||
T160 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y194 | Phosphorylation | score1 | PhosphoSitePlus | |||
K198 | Acetylation | score1 | PhosphoSitePlus | |||
K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
K223 | Acetylation | score1 | PhosphoSitePlus | |||
K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
C290 | Methylation | score1 | IEDB | 31844290 | ||
Y325 | Phosphorylation | score1 | PhosphoSitePlus | |||
T327 | Phosphorylation | score1 | PhosphoSitePlus | |||
K329 | Acetylation | score1 | PhosphoSitePlus | |||
S401 | Phosphorylation | score1 | PhosphoSitePlus | |||
K407 | Ubiquitination | score1 | PhosphoSitePlus | |||
T416 | Phosphorylation | score1 | PhosphoSitePlus | |||
T534 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S111 | N111 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T160 | M160 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
T534 | I534 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |