iPTMnet Report for Q9H9G7 (AGO3)
Protein Information
UniProt AC / UniProt ID | Q9H9G7 / AGO3_HUMAN |
Protein Name | Protein argonaute-3 |
Gene Name | Name: AGO3 Synonyms:EIF2C3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H9G7 |
PRO Name | protein argonaute-3 (human) |
Definition | A protein argonaute-3 that is encoded in the genome of human. |
Short Label | hAGO3 |
Category | organism-gene |
Q9H9G7 (AGO3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
S5 | Phosphorylation | score1 | PhosphoSitePlus | |||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
K89 | Ubiquitination | score1 | PhosphoSitePlus | |||
K174 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y189 | Phosphorylation | score1 | PhosphoSitePlus | |||
T275 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y317 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y323 | Phosphorylation | score1 | PhosphoSitePlus | |||
K336 | Ubiquitination | score1 | PhosphoSitePlus | |||
T338 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y339 | Phosphorylation | score1 | PhosphoSitePlus | |||
C345 | Methylation | score1 | IEDB | 31844290 | ||
C353 | Methylation | score1 | IEDB | 31844290 | ||
K356 | Ubiquitination | score1 | PhosphoSitePlus | |||
S363 | Phosphorylation | score1 | PhosphoSitePlus | |||
K367 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y421 | Phosphorylation | score1 | PhosphoSitePlus | |||
T445 | Phosphorylation | score1 | PhosphoSitePlus | |||
K480 | Ubiquitination | score1 | PhosphoSitePlus | |||
C491 | Methylation | score1 | IEDB | 31844290 | ||
K494 | Ubiquitination | score1 | PhosphoSitePlus | |||
T512 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y513 | Phosphorylation | score1 | PhosphoSitePlus | |||
S514 | Phosphorylation | score1 | PhosphoSitePlus | |||
T527 | Phosphorylation | score1 | PhosphoSitePlus | |||
K534 | Ubiquitination | score1 | PhosphoSitePlus | |||
K656 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y682 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y683 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y705 | Phosphorylation | score1 | PhosphoSitePlus | |||
C788 | Methylation | score1 | IEDB | 31844290 | ||
S825 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S829 | Phosphorylation | score1 | PhosphoSitePlus | |||
S832 | Phosphorylation | score1 | PhosphoSitePlus | |||
S835 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S5 | V5 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y323 | C323 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T338 | P338 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y339 | S339 | Biomuta | [ cosmic ] DOID:184 / bone cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
Y682 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S832 | L832 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |