iPTMnet Report for Q9H792 (PEAK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H792 / PEAK1_HUMAN
Protein Name Inactive tyrosine-protein kinase PEAK1
Gene Name Name: PEAK1
Synonyms:KIAA2002;
Organism Homo sapiens (Human)

PRO ID PR:Q9H792
DAG View
PRO Name inactive tyrosine-protein kinase PEAK1 (human)
Definition An inactive tyrosine-protein kinase PEAK1 that is encoded in the genome of human.
Short Label hPEAK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H792 (PEAK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S212 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
S281 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
T293 Phosphorylation PhosphoSitePlus
S359 Phosphorylation PhosphoSitePlus
S370 Phosphorylation HPRD   PhosphoSitePlus 19413330
S377 Phosphorylation PhosphoSitePlus
Y387 Phosphorylation PhosphoSitePlus
S389 Phosphorylation PhosphoSitePlus
Y462 Phosphorylation PhosphoSitePlus
Y475 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
S500 O-Glycosylation GlyGen 23301498, 34846842, 31492838, ...35254053, 34019948, 35289036
S501 O-Glycosylation GlyGen 23301498, 34846842, 31492838, ...35254053, 34019948, 35289036
S502 O-Glycosylation GlyGen 23301498, 31492838, 34019948, ...35289036, 35254053
S503 Phosphorylation HPRD   PhosphoSitePlus 18669648
T504 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
T510 O-Glycosylation GlyGen 23301498, 32938750, 31492838, ...35254053, 34019948, 35289036
T510 Phosphorylation HPRD   PhosphoSitePlus 18669648
S511 O-Glycosylation GlyGen 23301498, 31492838, 34019948, ...35289036, 35254053
S512 O-Glycosylation GlyGen 23301498, 31492838, 34019948, ...35289036, 35254053
T515 Phosphorylation HPRD   PhosphoSitePlus 18669648
S527 Phosphorylation PhosphoSitePlus
Y531 Phosphorylation PhosphoSitePlus   RLIMS-P 32681075
T539 Phosphorylation PhosphoSitePlus
S540 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648
K563 Acetylation PhosphoSitePlus
K567 Acetylation PhosphoSitePlus
S568 Phosphorylation HPRD   PhosphoSitePlus 19651622, 18669648
T571 Phosphorylation HPRD   PhosphoSitePlus 19413330, 19651622
S572 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 19651622, 18669648, ...23186163
T574 Phosphorylation HPRD   PhosphoSitePlus 19413330
T576 Phosphorylation PhosphoSitePlus
K581 Acetylation PhosphoSitePlus
S587 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18669648, 23186163
N589 N-Glycosylation GlyGen 29741879
Y598 Phosphorylation PhosphoSitePlus
T615 Phosphorylation PhosphoSitePlus
Y616 Phosphorylation PhosphoSitePlus
Y635 Phosphorylation P07948 (LYN) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18083107, 35687021, 20068231, ...23378338
Y641 Phosphorylation PhosphoSitePlus
S643 Phosphorylation PhosphoSitePlus
S648 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 19664994, 23186163
S652 Phosphorylation PhosphoSitePlus
T657 Phosphorylation PhosphoSitePlus
Y665 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 23105102
S719 Phosphorylation IEDB 32157095
S725 Phosphorylation PhosphoSitePlus
S729 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
T759 Phosphorylation PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus
T783 Phosphorylation PhosphoSitePlus
S786 Phosphorylation PhosphoSitePlus
S792 Phosphorylation PhosphoSitePlus
Y797 Phosphorylation PhosphoSitePlus
S812 Phosphorylation PhosphoSitePlus
T813 Phosphorylation PhosphoSitePlus
S819 Phosphorylation PhosphoSitePlus
T822 Phosphorylation PhosphoSitePlus
S826 Phosphorylation HPRD   PhosphoSitePlus 20068231
T834 Phosphorylation HPRD   PhosphoSitePlus 18669648
S837 Phosphorylation HPRD   PhosphoSitePlus 18669648
S847 Phosphorylation PhosphoSitePlus
T852 Phosphorylation PhosphoSitePlus
S854 Phosphorylation PhosphoSitePlus   UniProt 23186163
S856 Phosphorylation PhosphoSitePlus
T860 Phosphorylation PhosphoSitePlus
S861 Phosphorylation HPRD   PhosphoSitePlus 20068231
S864 Phosphorylation HPRD   PhosphoSitePlus 20068231
T876 Phosphorylation PhosphoSitePlus
S877 Phosphorylation PhosphoSitePlus
S878 Phosphorylation HPRD   PhosphoSitePlus 18669648
Y880 Phosphorylation PhosphoSitePlus
T897 Phosphorylation HPRD 20068231
S898 Phosphorylation PhosphoSitePlus   UniProt 23186163
T900 Phosphorylation PhosphoSitePlus
K921 Acetylation PhosphoSitePlus
S927 Phosphorylation PhosphoSitePlus
T937 Phosphorylation PhosphoSitePlus
T975 Phosphorylation PhosphoSitePlus
S981 Phosphorylation PhosphoSitePlus
S1001 Phosphorylation PhosphoSitePlus
S1028 Phosphorylation PhosphoSitePlus
S1035 Phosphorylation PhosphoSitePlus
S1036 Phosphorylation HPRD   PhosphoSitePlus 20068231
S1038 Phosphorylation HPRD   PhosphoSitePlus 17081983
S1046 Phosphorylation PhosphoSitePlus
S1057 Phosphorylation PhosphoSitePlus
T1074 Phosphorylation PhosphoSitePlus
T1077 Phosphorylation PhosphoSitePlus
T1078 Phosphorylation PhosphoSitePlus
S1104 Phosphorylation PhosphoSitePlus
T1106 Phosphorylation PhosphoSitePlus
Y1107 Phosphorylation PhosphoSitePlus
T1151 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 19664994, 24275569, ...23186163
T1165 Phosphorylation PhosphoSitePlus
Y1188 Phosphorylation UniProt 23846654
S1214 Phosphorylation PhosphoSitePlus
Y1215 Phosphorylation PhosphoSitePlus
S1217 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983
S1234 Phosphorylation PhosphoSitePlus
S1248 Phosphorylation PhosphoSitePlus
S1250 Phosphorylation PhosphoSitePlus
S1253 Phosphorylation PhosphoSitePlus
S1256 Phosphorylation PhosphoSitePlus
S1292 Phosphorylation PhosphoSitePlus
S1347 Phosphorylation HPRD   PhosphoSitePlus 18491316
Y1348 Phosphorylation HPRD   PhosphoSitePlus 18491316
Y1371 Phosphorylation PhosphoSitePlus
Y1372 Phosphorylation PhosphoSitePlus
S1374 Phosphorylation PhosphoSitePlus   UniProt 23186163
C1494 Methylation IEDB 31844290
S1563 Phosphorylation HPRD   PhosphoSitePlus 20068231
T1583 Phosphorylation PhosphoSitePlus
Y1587 Phosphorylation PhosphoSitePlus
S1657 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S212 N212 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S370 C370 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S503 P503 Biomuta DOID:1324 / lung cancer [ cosmic ]
T510 I510 Biomuta DOID:4159 / skin cancer [ cosmic ]
S511 L511 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
T571 I571 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S572 L572 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T615 A615 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S719 L719 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S786 A786 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S792 I792 Biomuta DOID:1324 / lung cancer [ cosmic ]
T813 M813 Biomuta [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T813 K813 Biomuta DOID:3571 / liver cancer [ cosmic ]
S854 T854 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S878 F878 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T897 A897 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S927 L927 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1028 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S1035 F1035 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1035 C1035 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1077 K1077 Biomuta DOID:3571 / liver cancer [ cosmic ]
T1077 P1077 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1078 A1078 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1106 A1106 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1106 I1106 Biomuta DOID:1319 / brain cancer [ icgc ]
Y1188 D1188 Biomuta DOID:263 / kidney cancer [ cosmic ]
S1217 F1217 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1253 F1253 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y1371 C1371 Biomuta DOID:263 / kidney cancer [ cosmic ]