iPTMnet Report Q9H792 PEAK1

Protein Information

UniProt AC / UniProt ID	Q9H792 / PEAK1_HUMAN
Protein Name	Inactive tyrosine-protein kinase PEAK1
Gene Name	Name: PEAK1 Synonyms:KIAA2002;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9H792 DAG View
PRO Name	inactive tyrosine-protein kinase PEAK1 (human)
Definition	An inactive tyrosine-protein kinase PEAK1 that is encoded in the genome of human.
Short Label	hPEAK1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9H792 (PEAK1) as Substrate

Q9H792

Condensed View

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position S212 S214 T279 S281 T293 S359 S370 S377 Y387 S389 Y462 Y475 S495 S500 S501 S502 S503 T504 S507 T510 S511 S512 T515 S527 Y531 T539 S540 K563 K567 S568 T571 S572 T574 T576 K581 S587 N589 Y598 T615 Y616 Y635 Y641 S643 S648 S652 T657 Y665 S719 S725 S729 S730 T759 S779 T783 S786 S792 Y797 S812 T813 S819 T822 S826 T834 S837 S847 T852 S854 S856 T860 S861 S864 T876 S877 S878 Y880 T897 S898 T900 K921 S927 T937 T975 S981 S1001 S1028 S1035 S1036 S1038 S1046 S1057 T1074 T1077 T1078 S1104 T1106 Y1107 T1151 T1165 Y1188 S1214 Y1215 S1217 S1234 S1248 S1250 S1253 S1256 S1292 S1347 Y1348 Y1371 Y1372 S1374 C1494 S1563 T1583 Y1587 S1657	PTM Type Select all Acetylation Methylation N-Glycosylation O-Glycosylation Phosphorylation	PTM Enzyme Select all P07948 (LYN)	Score Select all 0 1 2 3 4	Source Select all GlyGen HPRD IEDB PhosphoSitePlus RLIMS-P UniProt phospho.ELM	PMID
S212	Phosphorylation		score1	PhosphoSitePlus
S214	Phosphorylation		score1	PhosphoSitePlus
T279	Phosphorylation		score1	PhosphoSitePlus
S281	Phosphorylation		score2	HPRD phospho.ELM PhosphoSitePlus UniProt	23186163, 17081983, 20068231
T293	Phosphorylation		score1	PhosphoSitePlus
S359	Phosphorylation		score1	PhosphoSitePlus
S370	Phosphorylation		score2	HPRD PhosphoSitePlus	19413330
S377	Phosphorylation		score1	PhosphoSitePlus
Y387	Phosphorylation		score1	PhosphoSitePlus
S389	Phosphorylation		score1	PhosphoSitePlus
Y462	Phosphorylation		score1	PhosphoSitePlus
Y475	Phosphorylation		score1	PhosphoSitePlus
S495	Phosphorylation		score1	PhosphoSitePlus
S500	O-Glycosylation		score1	GlyGen	23301498, 34846842, 31492838, ...35254053, 34019948, 35289036
S501	O-Glycosylation		score1	GlyGen	23301498, 34846842, 31492838, ...35254053, 34019948, 35289036
S502	O-Glycosylation		score1	GlyGen	23301498, 31492838, 34019948, ...35289036, 35254053
S503	Phosphorylation		score2	HPRD PhosphoSitePlus	18669648
T504	Phosphorylation		score1	PhosphoSitePlus
S507	Phosphorylation		score1	PhosphoSitePlus
T510	O-Glycosylation		score1	GlyGen	23301498, 32938750, 31492838, ...35254053, 34019948, 35289036
T510	Phosphorylation		score2	HPRD PhosphoSitePlus	18669648
S511	O-Glycosylation		score1	GlyGen	23301498, 31492838, 34019948, ...35289036, 35254053
S512	O-Glycosylation		score1	GlyGen	23301498, 31492838, 34019948, ...35289036, 35254053
T515	Phosphorylation		score2	HPRD PhosphoSitePlus	18669648
S527	Phosphorylation		score1	PhosphoSitePlus
Y531	Phosphorylation		score3	PhosphoSitePlus RLIMS-P	32681075
T539	Phosphorylation		score1	PhosphoSitePlus
S540	Phosphorylation		score2	HPRD PhosphoSitePlus UniProt	18669648
K563	Acetylation		score1	PhosphoSitePlus
K567	Acetylation		score1	PhosphoSitePlus
S568	Phosphorylation		score2	HPRD PhosphoSitePlus	19651622, 18669648
T571	Phosphorylation		score2	HPRD PhosphoSitePlus	19413330, 19651622
S572	Phosphorylation		score2	HPRD PhosphoSitePlus UniProt	19413330, 19651622, 18669648, ...23186163
T574	Phosphorylation		score2	HPRD PhosphoSitePlus	19413330
T576	Phosphorylation		score1	PhosphoSitePlus
K581	Acetylation		score1	PhosphoSitePlus
S587	Phosphorylation		score2	HPRD PhosphoSitePlus UniProt	18669648, 23186163
N589	N-Glycosylation		score1	GlyGen	29741879
Y598	Phosphorylation		score1	PhosphoSitePlus
T615	Phosphorylation		score1	PhosphoSitePlus
Y616	Phosphorylation		score1	PhosphoSitePlus
Y635	Phosphorylation		score4	HPRD phospho.ELM PhosphoSitePlus RLIMS-P UniProt	18083107, 35687021, 20068231, ...23378338
Y635	Phosphorylation	P07948 (LYN)	score2	PhosphoSitePlus	23378338
Y641	Phosphorylation		score1	PhosphoSitePlus
S643	Phosphorylation		score1	PhosphoSitePlus
S648	Phosphorylation		score2	HPRD PhosphoSitePlus UniProt	19413330, 19664994, 23186163
S652	Phosphorylation		score1	PhosphoSitePlus
T657	Phosphorylation		score1	PhosphoSitePlus
Y665	Phosphorylation		score3	PhosphoSitePlus RLIMS-P UniProt	23105102
S719	Phosphorylation		score1	IEDB	32157095
S725	Phosphorylation		score1	PhosphoSitePlus
S729	Phosphorylation		score1	PhosphoSitePlus
S730	Phosphorylation		score1	PhosphoSitePlus
T759	Phosphorylation		score1	PhosphoSitePlus
S779	Phosphorylation		score1	PhosphoSitePlus
T783	Phosphorylation		score1	PhosphoSitePlus
S786	Phosphorylation		score1	PhosphoSitePlus
S792	Phosphorylation		score1	PhosphoSitePlus
Y797	Phosphorylation		score1	PhosphoSitePlus
S812	Phosphorylation		score1	PhosphoSitePlus
T813	Phosphorylation		score1	PhosphoSitePlus
S819	Phosphorylation		score1	PhosphoSitePlus
T822	Phosphorylation		score1	PhosphoSitePlus
S826	Phosphorylation		score2	HPRD PhosphoSitePlus	20068231
T834	Phosphorylation		score2	HPRD PhosphoSitePlus	18669648
S837	Phosphorylation		score2	HPRD PhosphoSitePlus	18669648
S847	Phosphorylation		score1	PhosphoSitePlus
T852	Phosphorylation		score1	PhosphoSitePlus
S854	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
S856	Phosphorylation		score1	PhosphoSitePlus
T860	Phosphorylation		score1	PhosphoSitePlus
S861	Phosphorylation		score2	HPRD PhosphoSitePlus	20068231
S864	Phosphorylation		score2	HPRD PhosphoSitePlus	20068231
T876	Phosphorylation		score1	PhosphoSitePlus
S877	Phosphorylation		score1	PhosphoSitePlus
S878	Phosphorylation		score2	HPRD PhosphoSitePlus	18669648
Y880	Phosphorylation		score1	PhosphoSitePlus
T897	Phosphorylation		score0	HPRD	20068231
S898	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
T900	Phosphorylation		score1	PhosphoSitePlus
K921	Acetylation		score1	PhosphoSitePlus
S927	Phosphorylation		score1	PhosphoSitePlus
T937	Phosphorylation		score1	PhosphoSitePlus
T975	Phosphorylation		score1	PhosphoSitePlus
S981	Phosphorylation		score1	PhosphoSitePlus
S1001	Phosphorylation		score1	PhosphoSitePlus
S1028	Phosphorylation		score1	PhosphoSitePlus
S1035	Phosphorylation		score1	PhosphoSitePlus
S1036	Phosphorylation		score2	HPRD PhosphoSitePlus	20068231
S1038	Phosphorylation		score2	HPRD PhosphoSitePlus	17081983
S1046	Phosphorylation		score1	PhosphoSitePlus
S1057	Phosphorylation		score1	PhosphoSitePlus
T1074	Phosphorylation		score1	PhosphoSitePlus
T1077	Phosphorylation		score1	PhosphoSitePlus
T1078	Phosphorylation		score1	PhosphoSitePlus
S1104	Phosphorylation		score1	PhosphoSitePlus
T1106	Phosphorylation		score1	PhosphoSitePlus
Y1107	Phosphorylation		score1	PhosphoSitePlus
T1151	Phosphorylation		score2	HPRD PhosphoSitePlus UniProt	19413330, 19664994, 24275569, ...23186163
T1165	Phosphorylation		score1	PhosphoSitePlus
Y1188	Phosphorylation		score2	UniProt	23846654
S1214	Phosphorylation		score1	PhosphoSitePlus
Y1215	Phosphorylation		score1	PhosphoSitePlus
S1217	Phosphorylation		score2	HPRD phospho.ELM PhosphoSitePlus	17081983
S1234	Phosphorylation		score1	PhosphoSitePlus
S1248	Phosphorylation		score1	PhosphoSitePlus
S1250	Phosphorylation		score1	PhosphoSitePlus
S1253	Phosphorylation		score1	PhosphoSitePlus
S1256	Phosphorylation		score1	PhosphoSitePlus
S1292	Phosphorylation		score1	PhosphoSitePlus
S1347	Phosphorylation		score2	HPRD PhosphoSitePlus	18491316
Y1348	Phosphorylation		score2	HPRD PhosphoSitePlus	18491316
Y1371	Phosphorylation		score1	PhosphoSitePlus
Y1372	Phosphorylation		score1	PhosphoSitePlus
S1374	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
C1494	Methylation		score1	IEDB	31844290
S1563	Phosphorylation		score2	HPRD PhosphoSitePlus	20068231
T1583	Phosphorylation		score1	PhosphoSitePlus
Y1587	Phosphorylation		score1	PhosphoSitePlus
S1657	Phosphorylation		score1	PhosphoSitePlus

PTM sites affected in variants

Search:

Site Select all By amino acid All Serine All Threonine All Tyrosine By position S212 S370 S503 T510 S511 T571 S572 T615 S719 S786 S792 T813 S854 S878 T897 S927 S1028 S1035 T1077 T1078 T1106 Y1188 S1217 S1253 Y1371	Variant Select all * A1078 A1106 A615 A786 A897 C1035 C1371 C370 D1188 F1035 F1217 F1253 F878 I1106 I510 I571 I792 K1077 K813 L511 L572 L719 L927 M813 N212 P1077 P503 T854	Source Select all Biomuta	Disease [Sample source] Select all DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:263 / kidney cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:5041 / esophageal cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S212	N212	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
S370	C370	Biomuta	DOID:8618 / oral cavity cancer [ cosmic ]
S503	P503	Biomuta	DOID:1324 / lung cancer [ cosmic ]
T510	I510	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S511	L511	Biomuta	DOID:5041 / esophageal cancer [ cosmic, icgc ]
T571	I571	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S572	L572	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ]
T615	A615	Biomuta	DOID:10534 / stomach cancer [ cosmic, icgc ]
S719	L719	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S786	A786	Biomuta	DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S792	I792	Biomuta	DOID:1324 / lung cancer [ cosmic ]
T813	M813	Biomuta	[ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
T813	K813	Biomuta	DOID:3571 / liver cancer [ cosmic ]
S854	T854	Biomuta	DOID:1319 / brain cancer [ cosmic, icgc ]
S878	F878	Biomuta	DOID:4159 / skin cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T897	A897	Biomuta	DOID:9256 / colorectal cancer [ cosmic ]
S927	L927	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S1028	*	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S1035	F1035	Biomuta	DOID:4159 / skin cancer [ cosmic ]
S1035	C1035	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
T1077	K1077	Biomuta	DOID:3571 / liver cancer [ cosmic ]
T1077	P1077	Biomuta	DOID:1324 / lung cancer [ cosmic, icgc ]
T1078	A1078	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ]
T1106	A1106	Biomuta	DOID:1324 / lung cancer [ cosmic ]
T1106	I1106	Biomuta	DOID:1319 / brain cancer [ icgc ]
Y1188	D1188	Biomuta	DOID:263 / kidney cancer [ cosmic ]
S1217	F1217	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ]
S1253	F1253	Biomuta	DOID:4159 / skin cancer [ cosmic, icgc ]
Y1371	C1371	Biomuta	DOID:263 / kidney cancer [ cosmic ]

PTM Type		Select All, None
Acetylation	N-Glycosylation	O-Glycosylation
C-Glycosylation	S-Glycosylation	Methylation
Myristoylation	Phosphorylation	Sumoylation
Ubiquitination	S-Nitrosylation

Select organisms		Select All, None
Human	Mouse	Rat
Cow	Chicken	Zebrafish
Fruit fly	C. elegans	Baker's yeast
Fission yeast	A. thaliana	Maize
M. truncatula	Rice (japonica)	Rice (indica)

Or input other organisms

iPTMnet Report for Q9H792 (PEAK1)

Protein Information

Interactive Sequence View

Q9H792 (PEAK1) as Substrate

PTM sites affected in variants