iPTMnet Report for Q9H492 (MAP1LC3A)
Protein Information
| UniProt AC / UniProt ID | Q9H492 / MLP3A_HUMAN |
| Protein Name | Microtubule-associated proteins 1A/1B light chain 3A precursor |
| Gene Name | Name: MAP1LC3A |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H492 |
| PRO Name | microtubule-associated proteins 1A/1B light chain 3A (human) |
| Definition | A microtubule-associated proteins 1A/1B light chain 3A that is encoded in the genome of human. |
| Short Label | hMAP1LC3A |
| Category | organism-gene |
DAG ViewQ9H492 (MAP1LC3A) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S12 | Phosphorylation | P17612 (PRKACA) | score3 | neXtProt PhosphoSitePlus RLIMS-P UniProt | 20713600 | |
| K42 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K49 | Acetylation | score1 | PhosphoSitePlus | |||
| K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T50 | Phosphorylation | Q13188 (STK3) , Q13043 (STK4) | score4 | RLIMS-P+ RLIMS-P | 25544559, 25996575 | |
| K51 | Acetylation | score1 | PhosphoSitePlus | |||
| S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S92 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T93 | Phosphorylation | score0 | RLIMS-P | 28085066 |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | P30086 (PEBP1) | S153 | Q9H492 (MAP1LC3A) | unknown | eFIP | 27540684 | |
| Phosphorylation | Q03181 (PPARD) | Y108 | Q9H492 (MAP1LC3A) | increased_association | eFIP | 32439863 | |
| Phosphorylation | Q96CV9 (OPTN) | S473 | Q9H492 (MAP1LC3A) | increased_association | eFIP | 33893090 | |
| Phosphorylation | Q9Y4P1 (ATG4B) | S316 | Q9H492 (MAP1LC3A) | decreased_association | eFIP | 28821708 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S87 | N87 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
