iPTMnet Report for Q9H492 (MAP1LC3A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H492 / MLP3A_HUMAN
Protein Name Microtubule-associated proteins 1A/1B light chain 3A precursor
Gene Name Name: MAP1LC3A
Organism Homo sapiens (Human)

PRO ID PR:Q9H492
DAG View
PRO Name microtubule-associated proteins 1A/1B light chain 3A (human)
Definition A microtubule-associated proteins 1A/1B light chain 3A that is encoded in the genome of human.
Short Label hMAP1LC3A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H492 (MAP1LC3A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 20713600
S12 Phosphorylation P17612 (PRKACA) neXtProt   PhosphoSitePlus 20713600
K42 Ubiquitination PhosphoSitePlus
K49 Acetylation PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
T50 Phosphorylation RLIMS-P+   RLIMS-P 25544559, 25996575
T50 Phosphorylation Q13043 (STK4) RLIMS-P+ 25544559
T50 Phosphorylation Q13188 (STK3) RLIMS-P+ 25544559
K51 Acetylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
T93 Phosphorylation RLIMS-P 28085066


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P30086 (PEBP1) S153 Q9H492 (MAP1LC3A) unknown eFIP 27540684
Phosphorylation Q03181 (PPARD) Y108 Q9H492 (MAP1LC3A) increased_association eFIP 32439863
Phosphorylation Q96CV9 (OPTN) S473 Q9H492 (MAP1LC3A) increased_association eFIP 33893090
Phosphorylation Q9Y4P1 (ATG4B) S316 Q9H492 (MAP1LC3A) decreased_association eFIP 28821708


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S87 N87 Biomuta DOID:9256 / colorectal cancer [ cosmic ]