iPTMnet Report for Q9H488 (POFUT1)
Protein Information
UniProt AC / UniProt ID | Q9H488 / OFUT1_HUMAN |
Protein Name | GDP-fucose protein O-fucosyltransferase 1 precursor |
Gene Name | Name: POFUT1 Synonyms:FUT12,KIAA0180; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H488 |
PRO Name | GDP-fucose protein O-fucosyltransferase 1 (human) |
Definition | A GDP-fucose protein O-fucosyltransferase 1 that is encoded in the genome of human. |
Short Label | hPOFUT1 |
Category | organism-gene |
Q9H488 (POFUT1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N62 | N-Glycosylation | score3 | GlyGen UniProt | 28334865 | ||
Y87 | Phosphorylation | score1 | PhosphoSitePlus | |||
K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
S104 | Phosphorylation | score1 | PhosphoSitePlus | |||
N160 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218 | ||
Y211 | Phosphorylation | score1 | PhosphoSitePlus | |||
K246 | Ubiquitination | score1 | PhosphoSitePlus | |||
K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
T310 | Phosphorylation | score1 | PhosphoSitePlus | |||
K324 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N62 | S62 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |