iPTMnet Report for Q9H488 (POFUT1)
Protein Information
| UniProt AC / UniProt ID | Q9H488 / OFUT1_HUMAN |
| Protein Name | GDP-fucose protein O-fucosyltransferase 1 precursor |
| Gene Name | Name: POFUT1 Synonyms:FUT12,KIAA0180; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H488 |
| PRO Name | GDP-fucose protein O-fucosyltransferase 1 (human) |
| Definition | A GDP-fucose protein O-fucosyltransferase 1 that is encoded in the genome of human. |
| Short Label | hPOFUT1 |
| Category | organism-gene |
Q9H488 (POFUT1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| N62 | N-Glycosylation | score3 | GlyGen UniProt | 28334865 | ||
| Y87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K92 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S104 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N160 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218 | ||
| Y211 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K246 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T310 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K324 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N62 | S62 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
DAG View