iPTMnet Report for Q9H257 (CARD9)
Protein Information
| UniProt AC / UniProt ID | Q9H257 / CARD9_HUMAN |
| Protein Name | Caspase recruitment domain-containing protein 9 |
| Gene Name | Name: CARD9 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9H257 |
| PRO Name | caspase recruitment domain-containing protein 9 (human) |
| Definition | A caspase recruitment domain-containing protein 9 that is encoded in the genome of human. |
| Short Label | hCARD9 |
| Category | organism-gene |
DAG ViewQ9H257 (CARD9) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K38 | Sumoylation | score1 | PhosphoSitePlus | |||
| Y76 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y86 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T95 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K125 | Ubiquitination | score4 | PhosphoSitePlus UniProt | 31296852, 33093067, 26488816 | ||
| T134 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S152 | O-Glycosylation | score1 | GlyGen | 34105348 | ||
| S152 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C178 | S-Nitrosylation | score0 | dbSNO | 24105792 | ||
| T231 | Phosphorylation | score3 | neXtProt PRO PhosphoSitePlus | 22265677 | ||
| T231 | Phosphorylation | Q05655 (PRKCD) | score3 | neXtProt PhosphoSitePlus | 22265677 | |
| S276 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S277 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| Y339 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S425 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S431 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S439 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S450 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S460 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18088087 | ||
| S483 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S498 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T531 | Phosphorylation | score3 | PhosphoSitePlus Signor | 17936701 | ||
| T531 | Phosphorylation | P68400 (CSNK2A1) | score3 | PhosphoSitePlus Signor | 17936701 | |
| T533 | Phosphorylation | score3 | PhosphoSitePlus Signor | 17936701 | ||
| T533 | Phosphorylation | P68400 (CSNK2A1) | score3 | PhosphoSitePlus Signor | 17936701 |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000046569 (hCARD9/Phos:1) | pT231 | PRO |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T95 | K95 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K125 | R125 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
| C178 | Y178 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| C178 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| T231 | M231 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S435 | P435 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S460 | G460 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] |
