Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H257 / CARD9_HUMAN
Protein Name Caspase recruitment domain-containing protein 9
Gene Name Name: CARD9
Organism Homo sapiens (Human)

PRO ID PR:Q9H257
DAG View
PRO Name caspase recruitment domain-containing protein 9 (human)
Definition A caspase recruitment domain-containing protein 9 that is encoded in the genome of human.
Short Label hCARD9
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H257 (CARD9) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K38 Sumoylation PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
T95 Phosphorylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
T134 Phosphorylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
C178 S-Nitrosylation dbSNO 24105792
T231 Phosphorylation Q05655 (PRKCD) neXtProt   PRO   PhosphoSitePlus 22265677
S276 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y339 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus   UniProt 23186163
S431 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
S450 Phosphorylation PhosphoSitePlus
S460 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087
S483 Phosphorylation PhosphoSitePlus   UniProt 23186163
S498 Phosphorylation PhosphoSitePlus   UniProt 23186163
T531 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 17936701
T533 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 17936701
Site PTM Type PTM Enzyme Score Source PMID
S460 Phosphorylation HPRD 18088087


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046569 (hCARD9/Phos:1) pT231 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T95 K95 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K125 R125 Biomuta DOID:3571 / liver cancer [ tcga ]
C178 * Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T231 M231 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S435 P435 Biomuta DOID:1324 / lung cancer [ cosmic ]