iPTMnet Report for Q9H0K6 (PUS7L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9H0K6 / PUS7L_HUMAN
Protein Name Pseudouridylate synthase PUS7L
Gene Name Name: PUS7L
Organism Homo sapiens (Human)

PRO ID PR:Q9H0K6
DAG View
PRO Name pseudouridylate synthase PUS7L (human)
Definition A pseudouridylate synthase 7-like protein that is encoded in the genome of human.
Short Label hPUS7L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9H0K6 (PUS7L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T5 Phosphorylation PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
S79 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y94 Phosphorylation PhosphoSitePlus
T95 Phosphorylation PhosphoSitePlus
S103 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K264 Methylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
K341 Acetylation PhosphoSitePlus
K352 Acetylation PhosphoSitePlus
K388 Methylation PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
K423 Ubiquitination PhosphoSitePlus
Y428 Phosphorylation PhosphoSitePlus
Y429 Phosphorylation PhosphoSitePlus
K459 Ubiquitination PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
K634 Ubiquitination PhosphoSitePlus
C640 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S79 L79 Biomuta DOID:4159 / skin cancer [ cosmic ]
K121 I121 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K264 E264 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
K401 Q401 Biomuta DOID:9256 / colorectal cancer [ cosmic ]