iPTMnet Report for Q9H0K6 (PUS7L)
Protein Information
UniProt AC / UniProt ID | Q9H0K6 / PUS7L_HUMAN |
Protein Name | Pseudouridylate synthase PUS7L |
Gene Name | Name: PUS7L |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9H0K6 |
PRO Name | pseudouridylate synthase PUS7L (human) |
Definition | A pseudouridylate synthase 7-like protein that is encoded in the genome of human. |
Short Label | hPUS7L |
Category | organism-gene |
Q9H0K6 (PUS7L) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T5 | Phosphorylation | score1 | PhosphoSitePlus | |||
T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
S79 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y94 | Phosphorylation | score1 | PhosphoSitePlus | |||
T95 | Phosphorylation | score1 | PhosphoSitePlus | |||
S103 | Phosphorylation | score1 | PhosphoSitePlus | |||
S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
K264 | Methylation | score1 | PhosphoSitePlus | |||
S293 | Phosphorylation | score1 | PhosphoSitePlus | |||
K338 | Ubiquitination | score1 | PhosphoSitePlus | |||
K341 | Acetylation | score1 | PhosphoSitePlus | |||
K352 | Acetylation | score1 | PhosphoSitePlus | |||
K388 | Methylation | score1 | PhosphoSitePlus | |||
K388 | Ubiquitination | score1 | PhosphoSitePlus | |||
K401 | Ubiquitination | score1 | PhosphoSitePlus | |||
K423 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y428 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y429 | Phosphorylation | score1 | PhosphoSitePlus | |||
K459 | Ubiquitination | score1 | PhosphoSitePlus | |||
K476 | Ubiquitination | score1 | PhosphoSitePlus | |||
K485 | Ubiquitination | score1 | PhosphoSitePlus | |||
S489 | Phosphorylation | score1 | PhosphoSitePlus | |||
K634 | Ubiquitination | score1 | PhosphoSitePlus | |||
C640 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S79 | L79 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K121 | I121 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K264 | E264 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
K401 | Q401 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |