Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9GZV5 / WWTR1_HUMAN
Protein Name WW domain-containing transcription regulator protein 1
Gene Name Name: WWTR1
Synonyms:TAZ;
Organism Homo sapiens (Human)

PRO ID PR:Q9GZV5
DAG View
PRO Name WW domain-containing transcription regulator protein 1 (human)
Definition A WW domain-containing transcription regulator protein 1 that is encoded in the genome of human.
Short Label hWWTR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9GZV5 (WWTR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K46 Ubiquitination PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
S62 Phosphorylation PhosphoSitePlus   UniProt 23186163
S65 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
T67 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
S87 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 17081983, ...20068231
S89 Phosphorylation O95835 (LATS1) , Q9NRM7 (LATS2) HPRD   neXtProt   PRO   PhosphoSitePlus   Signor   UniProt 21808241, 22658639, 20412773, ...11118213, 18227151, 20068231
S90 Phosphorylation P06493 (CDK1) HPRD   PhosphoSitePlus 26375055, 26183396, 17081983, ...20068231
S93 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
T98 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 20068231
S105 Phosphorylation P06493 (CDK1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 26375055, 26183396, ...20068231
S117 Phosphorylation HPRD   PhosphoSitePlus 20068231
Y118 Phosphorylation HPRD 20068231
S173 Phosphorylation PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
T285 Phosphorylation P06493 (CDK1) PhosphoSitePlus 26183396
S290 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus   UniProt 23186163
S307 Phosphorylation PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus   UniProt 18227151
T312 Phosphorylation PhosphoSitePlus
S314 Phosphorylation P48730 (CSNK1D) , P49674 (CSNK1E) PhosphoSitePlus   Signor 24715453
Y321 Phosphorylation PhosphoSitePlus
T326 Phosphorylation P06493 (CDK1) PhosphoSitePlus 26375055
T346 Phosphorylation P06493 (CDK1) PhosphoSitePlus 26375055
K392 Sumoylation PhosphoSitePlus
S393 Phosphorylation HPRD   PhosphoSitePlus 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049702 (hWWTR1/Phos:1) pS89 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S89 T89 Biomuta DOID:263 / kidney cancer [ cosmic ]
S89 A89 Biomuta DOID:0070003 / blastoma [ cosmic ]
S90 P90 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S290 F290 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
S307 L307 Biomuta DOID:1909 / melanoma [ cosmic ]
Y321 C321 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]