iPTMnet Report for Q9GZT9 (EGLN1)
Protein Information
UniProt AC / UniProt ID | Q9GZT9 / EGLN1_HUMAN |
Protein Name | Egl nine homolog 1 |
Gene Name | Name: EGLN1 Synonyms:C1orf12;ORFNames:PNAS-118,PNAS-137; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9GZT9 |
PRO Name | egl nine homolog 1 (human) |
Definition | An egl nine homolog 1 that is encoded in the genome of human. |
Short Label | hEGLN1 |
Category | organism-gene |
Q9GZT9 (EGLN1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 22814378 | ||
S5 | Phosphorylation | score1 | PhosphoSitePlus | |||
S12 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 23186163, 28199842 | ||
S14 | Phosphorylation | score0 | RLIMS-P | 28199842 | ||
S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
S125 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 35810304, 23186163, 28199842, ... | ||
C127 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
S136 | Phosphorylation | score1 | PhosphoSitePlus | |||
S174 | Phosphorylation | score1 | PhosphoSitePlus | |||
K216 | Ubiquitination | score1 | PhosphoSitePlus | |||
T232 | Phosphorylation | score1 | PhosphoSitePlus | |||
K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
K244 | Methylation | score1 | PhosphoSitePlus | |||
K244 | Ubiquitination | score1 | PhosphoSitePlus | |||
K255 | Ubiquitination | score1 | PhosphoSitePlus | |||
K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
K297 | Methylation | score1 | PhosphoSitePlus | |||
T308 | Phosphorylation | score1 | PhosphoSitePlus | |||
K337 | Ubiquitination | score1 | PhosphoSitePlus | |||
K350 | Ubiquitination | score1 | PhosphoSitePlus | |||
K402 | Ubiquitination | score1 | PhosphoSitePlus | |||
T405 | Phosphorylation | score1 | PhosphoSitePlus | |||
K408 | Acetylation | score1 | PhosphoSitePlus | |||
K408 | Ubiquitination | score1 | PhosphoSitePlus | |||
K416 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C127 | S127 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
S174 | N174 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K216 | N216 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K402 | T402 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
T405 | K405 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K416 | E416 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |