Protein Information

Cytoscape View

UniProt AC / UniProt ID Q9BXR0 / TGT_HUMAN
Protein Name Queuine tRNA-ribosyltransferase catalytic subunit 1
Gene Name Name: QTRT1
Organism Homo sapiens (Human)

DAG View
PRO Name queuine tRNA-ribosyltransferase catalytic subunit 1 (human)
Definition A queuine tRNA-ribosyltransferase catalytic subunit 1 that is encoded in the genome of human.
Short Label hQTRT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q9BXR0 (QTRT1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
S9 Phosphorylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus   UniProt 18847512, 23186163
S139 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
K219 Ubiquitination PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S231 Phosphorylation HPRD 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 F9 Biomuta DOID:11054 / urinary bladder cancer [ icgc, tcga ]
S139 N139 Biomuta DOID:363 / uterine cancer [ tcga ]