iPTMnet Report for Q9BXR0 (QTRT1)
Protein Information
| UniProt AC / UniProt ID | Q9BXR0 / TGT_HUMAN |
| Protein Name | Queuine tRNA-ribosyltransferase catalytic subunit 1 |
| Gene Name | Name: QTRT1 Synonyms:TGT,TGUT; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BXR0 |
| PRO Name | queuine tRNA-ribosyltransferase catalytic subunit 1 (human) |
| Definition | A queuine tRNA-ribosyltransferase catalytic subunit 1 that is encoded in the genome of human. |
| Short Label | hQTRT1 |
| Category | organism-gene |
Q9BXR0 (QTRT1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S12 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S139 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18847512, 23186163 | ||
| S139 | Phosphorylation | P24941 (CDK2) | score1 | PhosphoSitePlus | 18847512 | |
| K219 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S231 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S235 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K236 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C270 | Methylation | score1 | IEDB | 31844290 | ||
| K308 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K324 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K367 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S9 | F9 | Biomuta | DOID:11054 / urinary bladder cancer [ icgc ] | |
| S139 | N139 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| C270 | S270 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View