iPTMnet Report for Q9BXR0 (QTRT1)
Protein Information
UniProt AC / UniProt ID | Q9BXR0 / TGT_HUMAN |
Protein Name | Queuine tRNA-ribosyltransferase catalytic subunit 1 |
Gene Name | Name: QTRT1 Synonyms:TGT,TGUT; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BXR0 |
PRO Name | queuine tRNA-ribosyltransferase catalytic subunit 1 (human) |
Definition | A queuine tRNA-ribosyltransferase catalytic subunit 1 that is encoded in the genome of human. |
Short Label | hQTRT1 |
Category | organism-gene |
Q9BXR0 (QTRT1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378 | ||
S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
S12 | Phosphorylation | score1 | PhosphoSitePlus | |||
K55 | Ubiquitination | score1 | PhosphoSitePlus | |||
S139 | Phosphorylation | P24941 (CDK2) | score2 | PhosphoSitePlus UniProt | 18847512, 23186163 | |
K219 | Ubiquitination | score1 | PhosphoSitePlus | |||
S231 | Phosphorylation | score1 | PhosphoSitePlus | |||
S235 | Phosphorylation | score1 | PhosphoSitePlus | |||
K236 | Ubiquitination | score1 | PhosphoSitePlus | |||
C270 | Methylation | score1 | IEDB | 31844290 | ||
K308 | Ubiquitination | score1 | PhosphoSitePlus | |||
K324 | Ubiquitination | score1 | PhosphoSitePlus | |||
K367 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S9 | F9 | Biomuta | DOID:11054 / urinary bladder cancer [ icgc ] | |
S139 | N139 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
C270 | S270 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |