iPTMnet Report for Q9BV57 (ADI1)
Protein Information
UniProt AC / UniProt ID | Q9BV57 / MTND_HUMAN |
Protein Name | Acireductone dioxygenase |
Gene Name | Name: ADI1 Synonyms:MTCBP1;ORFNames:HMFT1638; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BV57 |
PRO Name | acireductone dioxygenase (human) |
Definition | An acireductone dioxygenase that is encoded in the genome of human. |
Short Label | hADI1 |
Category | organism-gene |
Q9BV57 (ADI1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R32 | Methylation | score1 | PhosphoSitePlus | |||
K40 | Ubiquitination | score1 | PhosphoSitePlus | |||
K45 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y46 | Phosphorylation | score1 | PhosphoSitePlus | |||
K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
K73 | Acetylation | score1 | PhosphoSitePlus | |||
K73 | Ubiquitination | score1 | PhosphoSitePlus | |||
K80 | Ubiquitination | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y104 | Phosphorylation | score1 | PhosphoSitePlus | |||
K110 | Ubiquitination | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
K173 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K54 | N54 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
Y104 | H104 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K144 | E144 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] |