Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BUB5 / MKNK1_HUMAN
Protein Name MAP kinase-interacting serine/threonine-protein kinase 1
Gene Name Name: MKNK1
Synonyms:MNK1;
Organism Homo sapiens (Human)

PRO ID PR:Q9BUB5
DAG View
PRO Name MAP kinase-interacting serine/threonine-protein kinase 1 (human)
Definition A MAP kinase-interacting serine/threonine-protein kinase 1 that is encoded in the genome of human.
Short Label hMKNK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BUB5 (MKNK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation Q13177 (PAK2) neXtProt   PhosphoSitePlus   Signor   UniProt 15234964, 23186163
Y60 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus   UniProt 23186163
S226 Phosphorylation PhosphoSitePlus   UniProt 23186163
S237 Phosphorylation PhosphoSitePlus
T250 Phosphorylation Q16539 (MAPK14) neXtProt   PRO   PhosphoSitePlus   Signor   UniProt 11463832, 17590453, 9155017
T255 Phosphorylation Q16539 (MAPK14) , P28482 (MAPK1) neXtProt   PRO   PhosphoSitePlus   Signor   UniProt 17130135, 11463832, 17590453, ...9155017
T385 Phosphorylation P27361 (MAPK3) neXtProt   phospho.ELM   PRO   PhosphoSitePlus   Signor   UniProt 9155018, 11463832, 23186163
S393 Phosphorylation PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PRO   PhosphoSitePlus
R455 Methylation PhosphoSitePlus
R459 Methylation PhosphoSitePlus
S460 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation Q13177 (PAK2) HPRD 15234964
S191 Phosphorylation HPRD 16162500
T250 Phosphorylation HPRD 15350534, 11154262
T255 Phosphorylation HPRD 15350534, 11154262
T385 Phosphorylation P27361 (MAPK3) HPRD 9155018
S437 Phosphorylation HPRD 16162500
S460 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T209 Phosphorylation Q16539 (MAPK14) PhosphoSitePlus 17590453
T214 Phosphorylation Q16539 (MAPK14) PhosphoSitePlus 17590453
S353 Phosphorylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S39 Phosphorylation Q13177 (PAK2) HPRD 15234964
T209 Phosphorylation HPRD 15350534, 11154262
T214 Phosphorylation HPRD 15350534, 11154262


Q9BUB5 (MKNK1) as PTM Enzyme



Substrate Site Score Source PMID
O43597 (SPRY2) S112 PhosphoSitePlus   Signor 16479008, 19864419
O43597 (SPRY2) S121 PhosphoSitePlus   Signor 16479008, 19864419
P06730 (EIF4E) S209 HPRD   PhosphoSitePlus   Signor 17130135, 11463832, 17590453, ...9878069, 17724079, 9155017
P09651 (HNRNPA1) S192 PhosphoSitePlus 16111636
P09651 (HNRNPA1) S362 PhosphoSitePlus 16111636
P09651 (HNRNPA1) S363 PhosphoSitePlus 16111636
P09651 (HNRNPA1) S364 PhosphoSitePlus 16111636
P23246 (SFPQ) S8 PhosphoSitePlus 17965020
P23246 (SFPQ) S283 PhosphoSitePlus 17965020
P47712 (PLA2G4A) S727 HPRD   Signor 16964243, 19664994, 18669648, ...10978317, 20068231, 18212344
Q9NP80 (PNPLA8) S511 PhosphoSitePlus 23258543


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048383 (hMKNK1/Phos:1) pT250,pT255,pT385,pS437 PRO