iPTMnet Report for Q9BRQ6 (CHCHD6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9BRQ6 / MIC25_HUMAN
Protein Name MICOS complex subunit MIC25
Gene Name Name: CHCHD6
Synonyms:CHCM1,MIC25;
Organism Homo sapiens (Human)

PRO ID PR:Q9BRQ6
DAG View
PRO Name MICOS complex subunit MIC25 (human)
Definition A MICOS complex subunit MIC25 that is encoded in the genome of human.
Short Label hCHCHD6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9BRQ6 (CHCHD6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20166139, 24275569
S42 Phosphorylation PhosphoSitePlus
S43 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T49 Phosphorylation PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
K84 Acetylation PhosphoSitePlus
K100 Acetylation PhosphoSitePlus
K106 Acetylation PhosphoSitePlus
K114 Acetylation PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K117 Acetylation PhosphoSitePlus
K133 Acetylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
T153 Phosphorylation PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
Y170 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
S186 Phosphorylation HPRD   PhosphoSitePlus 20068231
T187 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S42 I42 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
S43 F43 Biomuta DOID:4159 / skin cancer [ cosmic ]
K100 T100 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K156 N156 Biomuta DOID:1324 / lung cancer [ cosmic ]