iPTMnet Report for Q9BRQ6 (CHCHD6)
Protein Information
UniProt AC / UniProt ID | Q9BRQ6 / MIC25_HUMAN |
Protein Name | MICOS complex subunit MIC25 |
Gene Name | Name: CHCHD6 Synonyms:CHCM1,MIC25; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BRQ6 |
PRO Name | MICOS complex subunit MIC25 (human) |
Definition | A MICOS complex subunit MIC25 that is encoded in the genome of human. |
Short Label | hCHCHD6 |
Category | organism-gene |
Q9BRQ6 (CHCHD6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S13 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 20166139, 24275569 | ||
S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
S43 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648 | ||
T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
K65 | Ubiquitination | score1 | PhosphoSitePlus | |||
S67 | Phosphorylation | score1 | PhosphoSitePlus | |||
S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
K84 | Acetylation | score1 | PhosphoSitePlus | |||
K100 | Acetylation | score1 | PhosphoSitePlus | |||
K106 | Acetylation | score1 | PhosphoSitePlus | |||
K114 | Acetylation | score1 | PhosphoSitePlus | |||
K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
K117 | Acetylation | score1 | PhosphoSitePlus | |||
K133 | Acetylation | score1 | PhosphoSitePlus | |||
S134 | Phosphorylation | score1 | PhosphoSitePlus | |||
T153 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y155 | Phosphorylation | score1 | PhosphoSitePlus | |||
K156 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y170 | Phosphorylation | score1 | PhosphoSitePlus | |||
S173 | Phosphorylation | score1 | PhosphoSitePlus | |||
S186 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
T187 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S42 | I42 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
S43 | F43 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K100 | T100 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K156 | N156 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |