iPTMnet Report for Q9BQ69 (MACROD1)
Protein Information
| UniProt AC / UniProt ID | Q9BQ69 / MACD1_HUMAN |
| Protein Name | ADP-ribose glycohydrolase MACROD1 |
| Gene Name | Name: MACROD1 Synonyms:LRP16; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9BQ69 |
| PRO Name | ADP-ribose glycohydrolase MACROD1 (human) |
| Definition | An ADP-ribose glycohydrolase MACROD1 that is encoded in the genome of human. |
| Short Label | hMACROD1 |
| Category | organism-gene |
Q9BQ69 (MACROD1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T91 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
| K96 | Acetylation | score1 | PhosphoSitePlus | |||
| K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K103 | Acetylation | score1 | PhosphoSitePlus | |||
| K138 | Sumoylation | score1 | PhosphoSitePlus | |||
| K163 | Acetylation | score1 | PhosphoSitePlus | |||
| C199 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| R244 | Methylation | score1 | PhosphoSitePlus | |||
| C246 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| K309 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T91 | N91 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| R244 | H244 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| C246 | Y246 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| C246 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] |
DAG View