iPTMnet Report for Q9BQ69 (MACROD1)
Protein Information
UniProt AC / UniProt ID | Q9BQ69 / MACD1_HUMAN |
Protein Name | ADP-ribose glycohydrolase MACROD1 |
Gene Name | Name: MACROD1 Synonyms:LRP16; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9BQ69 |
PRO Name | ADP-ribose glycohydrolase MACROD1 (human) |
Definition | An ADP-ribose glycohydrolase MACROD1 that is encoded in the genome of human. |
Short Label | hMACROD1 |
Category | organism-gene |
Q9BQ69 (MACROD1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T91 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
K96 | Acetylation | score1 | PhosphoSitePlus | |||
K96 | Ubiquitination | score1 | PhosphoSitePlus | |||
K103 | Acetylation | score1 | PhosphoSitePlus | |||
K138 | Sumoylation | score1 | PhosphoSitePlus | |||
K163 | Acetylation | score1 | PhosphoSitePlus | |||
C199 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
R244 | Methylation | score1 | PhosphoSitePlus | |||
C246 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K309 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T91 | N91 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
R244 | H244 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
C246 | Y246 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
C246 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] |