iPTMnet Report for Q99962 (SH3GL2)
Protein Information
UniProt AC / UniProt ID | Q99962 / SH3G2_HUMAN |
Protein Name | Endophilin-A1 |
Gene Name | Name: SH3GL2 Synonyms:CNSA2,SH3D2A; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q99962 |
PRO Name | endophilin-A1 (human) |
Definition | An endophilin-A1 that is encoded in the genome of human. |
Short Label | hSH3GL2 |
Category | organism-gene |
Q99962 (SH3GL2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
T14 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P Signor | 16164598 | ||
T14 | Phosphorylation | O75116 (ROCK2) | score3 | PhosphoSitePlus Signor | 16164598 | |
S75 | Phosphorylation | score4 | HPRD phospho.ELM RLIMS-P Signor | 24778241, 17081983, 22998870 | ||
S75 | Phosphorylation | Q5S007 (LRRK2) | score1 | Signor | 22998870 | |
K76 | Acetylation | score1 | PhosphoSitePlus | |||
K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
K159 | Ubiquitination | score1 | PhosphoSitePlus | |||
K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
R184 | Methylation | score1 | PhosphoSitePlus | |||
S249 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K76 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
K177 | R177 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
R184 | C184 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
R184 | H184 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] |