Protein Information

Cytoscape View

UniProt AC / UniProt ID Q99962 / SH3G2_HUMAN
Protein Name Endophilin-A1
Gene Name Name: SH3GL2
Organism Homo sapiens (Human)

PRO ID PR:Q99962
DAG View
PRO Name endophilin-A1 (human)
Definition An endophilin-A1 that is encoded in the genome of human.
Short Label hSH3GL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q99962 (SH3GL2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
T14 Phosphorylation O75116 (ROCK2) PhosphoSitePlus   RLIMS-P   Signor 16164598
S75 Phosphorylation Q5S007 (LRRK2) HPRD   phospho.ELM   RLIMS-P   Signor 24778241, 17081983, 22998870
K76 Acetylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K159 Ubiquitination PhosphoSitePlus
K177 Ubiquitination PhosphoSitePlus
R184 Methylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K177 R177 Biomuta DOID:263 / kidney cancer [ cosmic, tcga ]
R184 C184 Biomuta DOID:1909 / melanoma [ tcga ]
R184 H184 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ tcga ]
R184 L184 Biomuta DOID:3571 / liver cancer [ icgc ]