iPTMnet Report for Q99962 (SH3GL2)
Protein Information
| UniProt AC / UniProt ID | Q99962 / SH3G2_HUMAN |
| Protein Name | Endophilin-A1 |
| Gene Name | Name: SH3GL2 Synonyms:CNSA2,SH3D2A; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q99962 |
| PRO Name | endophilin-A1 (human) |
| Definition | An endophilin-A1 that is encoded in the genome of human. |
| Short Label | hSH3GL2 |
| Category | organism-gene |
DAG ViewQ99962 (SH3GL2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T14 | Phosphorylation | O75116 (ROCK2) | score3 | PhosphoSitePlus RLIMS-P Signor | 16164598 | |
| S75 | Phosphorylation | Q5S007 (LRRK2) | score4 | HPRD phospho.ELM RLIMS-P Signor | 24778241, 17081983, 22998870 | |
| K76 | Acetylation | score1 | PhosphoSitePlus | |||
| K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K159 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R184 | Methylation | score1 | PhosphoSitePlus | |||
| S249 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K76 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| K177 | R177 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
| R184 | C184 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| R184 | H184 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] |
