iPTMnet Report for Q99801 (NKX3-1)
Protein Information
| UniProt AC / UniProt ID | Q99801 / NKX31_HUMAN |
| Protein Name | Homeobox protein Nkx-3.1 |
| Gene Name | Name: NKX3-1 Synonyms:NKX3.1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q99801 |
| PRO Name | homeobox protein Nkx-3.1 (human) |
| Definition | A homeobox protein Nkx-3.1 that is encoded in the genome of human. |
| Short Label | hNKX3-1 |
| Category | organism-gene |
DAG ViewQ99801 (NKX3-1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S48 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P Signor | 11980664 | ||
| S48 | Phosphorylation | P17252 (PRKCA) | score3 | PhosphoSitePlus Signor | 11980664 | |
| T89 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P Signor | 16581776, 23129228 | ||
| T89 | Phosphorylation | P11309 (PIM1) | score2 | PhosphoSitePlus | 23129228 | |
| T89 | Phosphorylation | P19784 (CSNK2A2) | score3 | PhosphoSitePlus Signor | 16581776 | |
| T93 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P Signor | 16581776 | ||
| T93 | Phosphorylation | P19784 (CSNK2A2) | score3 | PhosphoSitePlus Signor | 16581776 | |
| T134 | Phosphorylation | score2 | PhosphoSitePlus | 23890999 | ||
| T134 | Phosphorylation | Q13315 (ATM) | score2 | PhosphoSitePlus | 23890999 | |
| K159 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K162 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T166 | Phosphorylation | score2 | PhosphoSitePlus | 23890999 | ||
| T166 | Phosphorylation | Q13315 (ATM) | score2 | PhosphoSitePlus | 23890999 | |
| K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S185 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P+ RLIMS-P | 25777618, 23129228 | ||
| S185 | Phosphorylation | P11309 (PIM1) | score2 | PhosphoSitePlus | 23129228 | |
| S185 | Phosphorylation | Q9Y463 (DYRK1B) | score2 | RLIMS-P+ | 25777618 | |
| S186 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 23129228 | ||
| S186 | Phosphorylation | P11309 (PIM1) | score2 | PhosphoSitePlus | 23129228 | |
| S195 | Phosphorylation | score2 | PhosphoSitePlus | 23129228 | ||
| S195 | Phosphorylation | P11309 (PIM1) | score2 | PhosphoSitePlus | 23129228 | |
| S196 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P | 18757402, 23129228 | ||
| S196 | Phosphorylation | P11309 (PIM1) | score2 | PhosphoSitePlus | 23129228 | |
| Y222 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 23890999 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T134 | I134 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
| K182 | M182 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S186 | L186 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| S195 | F195 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S196 | F196 | Biomuta | DOID:1612 / breast cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic, icgc ] |
