iPTMnet Report for Q99536 (VAT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q99536 / VAT1_HUMAN
Protein Name Synaptic vesicle membrane protein VAT-1 homolog
Gene Name Name: VAT1
Organism Homo sapiens (Human)

PRO ID PR:Q99536
DAG View
PRO Name synaptic vesicle membrane protein VAT-1 homolog (human)
Definition A synaptic vesicle membrane protein VAT-1 that is encoded in the genome of human.
Short Label hVAT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q99536 (VAT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
S2 Phosphorylation PhosphoSitePlus
S17 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S18 Phosphorylation PhosphoSitePlus   UniProt 20068231, 24275569
K22 Ubiquitination PhosphoSitePlus
T23 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus   UniProt 24275569
S35 Phosphorylation PhosphoSitePlus   UniProt 24275569
S44 Phosphorylation PhosphoSitePlus   UniProt 24275569
R49 Methylation PhosphoSitePlus
C50 S-Nitrosylation dbSNO 19483679
Y59 Phosphorylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
T80 Phosphorylation PhosphoSitePlus
R102 Methylation PhosphoSitePlus
T109 Phosphorylation PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus
T220 Phosphorylation PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
Y240 Phosphorylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K271 Acetylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
K277 Ubiquitination PhosphoSitePlus
K295 Acetylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
K382 Ubiquitination PhosphoSitePlus
K391 Acetylation PhosphoSitePlus
K391 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation HPRD 18669648
S18 Phosphorylation HPRD 19413330, 20068231
S44 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S17 F17 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T23 I23 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S44 L44 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
R49 C49 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
Y240 C240 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K382 N382 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]