iPTMnet Report for Q99536 (VAT1)
Protein Information
UniProt AC / UniProt ID | Q99536 / VAT1_HUMAN |
Protein Name | Synaptic vesicle membrane protein VAT-1 homolog |
Gene Name | Name: VAT1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q99536 |
PRO Name | synaptic vesicle membrane protein VAT-1 homolog (human) |
Definition | A synaptic vesicle membrane protein VAT-1 that is encoded in the genome of human. |
Short Label | hVAT1 |
Category | organism-gene |
Q99536 (VAT1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 19413330 | ||
S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
S17 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S18 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231, 24275569 | ||
K22 | Ubiquitination | score1 | PhosphoSitePlus | |||
T23 | Phosphorylation | score1 | PhosphoSitePlus | |||
S27 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S35 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S44 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
R49 | Methylation | score1 | PhosphoSitePlus | |||
C50 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
Y59 | Phosphorylation | score1 | PhosphoSitePlus | |||
K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
T80 | Phosphorylation | score1 | PhosphoSitePlus | |||
R102 | Methylation | score1 | PhosphoSitePlus | |||
T109 | Phosphorylation | score1 | PhosphoSitePlus | |||
T211 | Phosphorylation | score1 | PhosphoSitePlus | |||
T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
K230 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y240 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y245 | Phosphorylation | score1 | PhosphoSitePlus | |||
K250 | Ubiquitination | score1 | PhosphoSitePlus | |||
K255 | Ubiquitination | score1 | PhosphoSitePlus | |||
K271 | Acetylation | score1 | PhosphoSitePlus | |||
K271 | Ubiquitination | score1 | PhosphoSitePlus | |||
K277 | Ubiquitination | score1 | PhosphoSitePlus | |||
K295 | Acetylation | score1 | PhosphoSitePlus | |||
K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
K355 | Ubiquitination | score1 | PhosphoSitePlus | |||
K366 | Ubiquitination | score1 | PhosphoSitePlus | |||
K372 | Ubiquitination | score1 | PhosphoSitePlus | |||
K382 | Ubiquitination | score1 | PhosphoSitePlus | |||
K391 | Acetylation | score1 | PhosphoSitePlus | |||
K391 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S17 | F17 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T23 | I23 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S44 | L44 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
R49 | C49 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
Y240 | C240 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
K382 | N382 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |