iPTMnet Report for Q99518 (FMO2)
Protein Information
UniProt AC / UniProt ID | Q99518 / FMO2_HUMAN |
Protein Name | Flavin-containing monooxygenase 2 |
Gene Name | Name: FMO2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q99518 |
PRO Name | flavin-containing monooxygenase 2 (human) |
Definition | A flavin-containing monooxygenase 2 that is encoded in the genome of human. |
Short Label | hFMO2 |
Category | organism-gene |
Q99518 (FMO2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
S17 | Phosphorylation | score1 | PhosphoSitePlus | |||
S57 | Phosphorylation | score1 | PhosphoSitePlus | |||
T129 | Phosphorylation | score1 | PhosphoSitePlus | |||
S131 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y170 | Phosphorylation | score1 | PhosphoSitePlus | |||
S195 | Phosphorylation | score1 | PhosphoSitePlus | |||
S241 | Phosphorylation | score1 | PhosphoSitePlus | |||
T250 | Phosphorylation | score1 | PhosphoSitePlus | |||
K492 | Sumoylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S17 | Y17 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S57 | C57 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
S131 | I131 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S195 | L195 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] | |
K492 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] |