iPTMnet Report for Q96S52 (PIGS)
Protein Information
UniProt AC / UniProt ID | Q96S52 / PIGS_HUMAN |
Protein Name | GPI transamidase component PIG-S |
Gene Name | Name: PIGS ORFNames:UNQ1873/PRO4316; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96S52 |
PRO Name | GPI transamidase component PIG-S (human) |
Definition | A GPI transamidase component PIG-S that is encoded in the genome of human. |
Short Label | hPIGS |
Category | organism-gene |
Q96S52 (PIGS) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K81 | Ubiquitination | score1 | PhosphoSitePlus | |||
K95 | Ubiquitination | score1 | PhosphoSitePlus | |||
K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
K217 | Acetylation | score1 | PhosphoSitePlus | |||
Y244 | Phosphorylation | score1 | PhosphoSitePlus | |||
S353 | Phosphorylation | score1 | PhosphoSitePlus | |||
T368 | O-Glycosylation | score1 | GlyGen | 34846842, 28510447, 30059200, ... | ||
N370 | N-Glycosylation | score1 | GlyGen | 29741879, 24190977 | ||
S372 | O-Glycosylation | score1 | GlyGen | 34846842, 28510447, 30059200, ... | ||
T437 | Phosphorylation | score1 | PhosphoSitePlus | |||
T439 | Phosphorylation | score1 | PhosphoSitePlus | |||
T440 | Phosphorylation | score1 | PhosphoSitePlus | |||
K458 | Ubiquitination | score1 | PhosphoSitePlus | |||
K467 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K95 | R95 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T440 | I440 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |