iPTMnet Report for Q96S44 (TP53RK)
Protein Information
| UniProt AC / UniProt ID | Q96S44 / PRPK_HUMAN |
| Protein Name | EKC/KEOPS complex subunit TP53RK |
| Gene Name | Name: TP53RK Synonyms:C20orf64,PRPK; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96S44 |
| PRO Name | EKC/KEOPS complex subunit TP53RK (human) |
| Definition | An EKC/KEOPS complex subunit TP53RK that is encoded in the genome of human. |
| Short Label | hTP53RK |
| Category | organism-gene |
DAG ViewQ96S44 (TP53RK) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T7 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18691976 | ||
| T8 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S34 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
| K40 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R68 | Methylation | score1 | PhosphoSitePlus | |||
| K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T135 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18691976, 19369195 | ||
| S140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y201 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S250 | Phosphorylation | score4 | neXtProt PhosphoSitePlus RLIMS-P Signor | 17712528, 28412249 | ||
| S250 | Phosphorylation | P31749 (AKT1) | score3 | neXtProt PhosphoSitePlus Signor | 17712528 |
Q96S44 (TP53RK) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| P04637 (TP53) | S15 | score4 | PhosphoSitePlus Signor | 17712528, 11546806 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| R68 | G68 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| K144 | R144 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| Y201 | H201 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] |
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