Protein Information

Cytoscape View

UniProt AC / UniProt ID Q96S44 / PRPK_HUMAN
Protein Name EKC/KEOPS complex subunit TP53RK
Gene Name Name: TP53RK
Organism Homo sapiens (Human)

DAG View
PRO Name EKC/KEOPS complex subunit TP53RK (human)
Definition An EKC/KEOPS complex subunit TP53RK that is encoded in the genome of human.
Short Label hTP53RK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

Q96S44 (TP53RK) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation HPRD   PhosphoSitePlus 18691976
T8 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus   UniProt 19369195
K40 Ubiquitination PhosphoSitePlus
R68 Methylation PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
T135 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 19369195
S140 Phosphorylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
Y201 Phosphorylation PhosphoSitePlus
S250 Phosphorylation P31749 (AKT1) neXtProt   PhosphoSitePlus   RLIMS-P   Signor 17712528, 28412249

Q96S44 (TP53RK) as PTM Enzyme

Substrate Site Score Source PMID
P04637 (TP53) S15 PhosphoSitePlus   Signor 17712528, 11546806

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R68 G68 Biomuta DOID:2531 / hematologic cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
Y201 H201 Biomuta DOID:2531 / hematologic cancer [ icgc ]