iPTMnet Report for Q96PE3 (INPP4A)
Protein Information
| UniProt AC / UniProt ID | Q96PE3 / INP4A_HUMAN |
| Protein Name | Inositol polyphosphate-4-phosphatase type I A |
| Gene Name | Name: INPP4A |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96PE3 |
| PRO Name | inositol polyphosphate-4-phosphatase type I A (human) |
| Definition | An inositol polyphosphate-4-phosphatase type I A that is encoded in the genome of human. |
| Short Label | hINPP4A |
| Category | organism-gene |
Q96PE3 (INPP4A) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T22 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T137 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R147 | Methylation | score1 | PhosphoSitePlus | |||
| K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S214 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T219 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C230 | Methylation | score1 | IEDB | 31844290 | ||
| S252 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K321 | Methylation | score1 | PhosphoSitePlus | |||
| K330 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y355 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15592455 | ||
| K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T394 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S395 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K412 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y427 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S433 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K454 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K465 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y481 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K485 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S487 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332 | ||
| S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S514 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S517 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K536 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K547 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K551 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C687 | Methylation | score1 | IEDB | 31844290 | ||
| K745 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T747 | O-Glycosylation | score1 | GlyGen | 30379171, 29351928 | ||
| S851 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T942 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y951 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S955 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K959 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K963 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y965 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y972 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K974 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T137 | Phosphorylation | score0 | HPRD | 18491316 | ||
| S916 | Phosphorylation | score0 | HPRD | 20068231 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K387 | Ubiquitination | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| T137 | Phosphorylation | score0 | HPRD | 18491316 | ||
| S908 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C230 | Y230 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K387 | R387 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S395 | L395 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K412 | R412 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| Y481 | S481 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S490 | L490 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] | |
| S514 | N514 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| C687 | F687 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K745 | T745 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| T942 | A942 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| Y972 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K974 | Q974 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
DAG View