iPTMnet Report for Q96PE3 (INPP4A)
Protein Information
UniProt AC / UniProt ID | Q96PE3 / INP4A_HUMAN |
Protein Name | Inositol polyphosphate-4-phosphatase type I A |
Gene Name | Name: INPP4A |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96PE3 |
PRO Name | inositol polyphosphate-4-phosphatase type I A (human) |
Definition | An inositol polyphosphate-4-phosphatase type I A that is encoded in the genome of human. |
Short Label | hINPP4A |
Category | organism-gene |
Q96PE3 (INPP4A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
T22 | Phosphorylation | score1 | PhosphoSitePlus | |||
K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
T137 | Phosphorylation | score1 | PhosphoSitePlus | |||
R147 | Methylation | score1 | PhosphoSitePlus | |||
K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
S214 | Phosphorylation | score1 | PhosphoSitePlus | |||
T219 | Phosphorylation | score1 | PhosphoSitePlus | |||
K222 | Ubiquitination | score1 | PhosphoSitePlus | |||
C230 | Methylation | score1 | IEDB | 31844290 | ||
S252 | Phosphorylation | score1 | PhosphoSitePlus | |||
K321 | Methylation | score1 | PhosphoSitePlus | |||
K330 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y355 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15592455 | ||
K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
T394 | Phosphorylation | score1 | PhosphoSitePlus | |||
S395 | Phosphorylation | score1 | PhosphoSitePlus | |||
K412 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y427 | Phosphorylation | score1 | PhosphoSitePlus | |||
S433 | Phosphorylation | score1 | PhosphoSitePlus | |||
K454 | Ubiquitination | score1 | PhosphoSitePlus | |||
K465 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y481 | Phosphorylation | score1 | PhosphoSitePlus | |||
K485 | Ubiquitination | score1 | PhosphoSitePlus | |||
S487 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 19690332 | ||
S490 | Phosphorylation | score1 | PhosphoSitePlus | |||
S514 | Phosphorylation | score1 | PhosphoSitePlus | |||
S517 | Phosphorylation | score1 | PhosphoSitePlus | |||
K536 | Ubiquitination | score1 | PhosphoSitePlus | |||
K547 | Ubiquitination | score1 | PhosphoSitePlus | |||
K551 | Ubiquitination | score1 | PhosphoSitePlus | |||
C687 | Methylation | score1 | IEDB | 31844290 | ||
K745 | Ubiquitination | score1 | PhosphoSitePlus | |||
T747 | O-Glycosylation | score1 | GlyGen | 30379171, 29351928 | ||
S851 | Phosphorylation | score1 | PhosphoSitePlus | |||
T942 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y951 | Phosphorylation | score1 | PhosphoSitePlus | |||
S955 | Phosphorylation | score1 | PhosphoSitePlus | |||
K959 | Ubiquitination | score1 | PhosphoSitePlus | |||
K963 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y965 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y972 | Phosphorylation | score1 | PhosphoSitePlus | |||
K974 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T137 | Phosphorylation | score0 | HPRD | 18491316 | ||
S916 | Phosphorylation | score0 | HPRD | 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K387 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T137 | Phosphorylation | score0 | HPRD | 18491316 | ||
S908 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C230 | Y230 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K387 | R387 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S395 | L395 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K412 | R412 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
Y481 | S481 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S490 | L490 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] | |
S514 | N514 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
C687 | F687 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K745 | T745 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
T942 | A942 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
Y972 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K974 | Q974 | Biomuta | DOID:363 / uterine cancer [ icgc ] |