iPTMnet Report for Q96MM7 (HS6ST2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96MM7 / H6ST2_HUMAN
Protein Name Heparan-sulfate 6-O-sulfotransferase 2
Gene Name Name: HS6ST2
ORFNames:PSEC0092;
Organism Homo sapiens (Human)

PRO ID PR:Q96MM7
DAG View
PRO Name heparan-sulfate 6-O-sulfotransferase 2 (human)
Definition A heparan-sulfate 6-O-sulfotransferase 2 that is encoded in the genome of human.
Short Label hHS6ST2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96MM7 (HS6ST2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S75 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
K218 Methylation PhosphoSitePlus
T398 O-Glycosylation GlyGen 29237092, 35254053
T398 Phosphorylation PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
T457 Phosphorylation PhosphoSitePlus
Y459 Phosphorylation PhosphoSitePlus
T461 Phosphorylation PhosphoSitePlus
T462 Phosphorylation PhosphoSitePlus
T528 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S591 O-Glycosylation GlyGen 29237092, 35254053
S591 Phosphorylation PhosphoSitePlus
T594 Phosphorylation PhosphoSitePlus
S600 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S406 C406 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T461 I461 Biomuta DOID:1319 / brain cancer [ icgc ]
T462 I462 Biomuta DOID:363 / uterine cancer [ icgc ]