iPTMnet Report for Q96MM7 (HS6ST2)
Protein Information
UniProt AC / UniProt ID | Q96MM7 / H6ST2_HUMAN |
Protein Name | Heparan-sulfate 6-O-sulfotransferase 2 |
Gene Name | Name: HS6ST2 ORFNames:PSEC0092; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96MM7 |
PRO Name | heparan-sulfate 6-O-sulfotransferase 2 (human) |
Definition | A heparan-sulfate 6-O-sulfotransferase 2 that is encoded in the genome of human. |
Short Label | hHS6ST2 |
Category | organism-gene |
Q96MM7 (HS6ST2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
S76 | Phosphorylation | score1 | PhosphoSitePlus | |||
S77 | Phosphorylation | score1 | PhosphoSitePlus | |||
S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
K218 | Methylation | score1 | PhosphoSitePlus | |||
T398 | O-Glycosylation | score1 | GlyGen | 29237092, 35254053 | ||
T398 | Phosphorylation | score1 | PhosphoSitePlus | |||
S406 | Phosphorylation | score1 | PhosphoSitePlus | |||
T457 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y459 | Phosphorylation | score1 | PhosphoSitePlus | |||
T461 | Phosphorylation | score1 | PhosphoSitePlus | |||
T462 | Phosphorylation | score1 | PhosphoSitePlus | |||
T528 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
S591 | O-Glycosylation | score1 | GlyGen | 29237092, 35254053 | ||
S591 | Phosphorylation | score1 | PhosphoSitePlus | |||
T594 | Phosphorylation | score1 | PhosphoSitePlus | |||
S600 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S406 | C406 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
T461 | I461 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
T462 | I462 | Biomuta | DOID:363 / uterine cancer [ icgc ] |