iPTMnet Report for Q96K21 (ZFYVE19)
Protein Information
UniProt AC / UniProt ID | Q96K21 / ANCHR_HUMAN |
Protein Name | Abscission/NoCut checkpoint regulator |
Gene Name | Name: ZFYVE19 Synonyms:ANCHR,MPFYVE; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96K21 |
PRO Name | abscission/NoCut checkpoint regulator (human) |
Definition | An abscission/NoCut checkpoint regulator that is encoded in the genome of human. |
Short Label | hZFYVE19 |
Category | organism-gene |
Q96K21 (ZFYVE19) as Substrate
Site | PTM Type | PTM Enzyme |
Score
| Source | PMID | |
---|---|---|---|---|---|---|
Y3 | Phosphorylation | score1 | PhosphoSitePlus | |||
S5 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y15 | Phosphorylation | score1 | PhosphoSitePlus | |||
S22 | Phosphorylation | score1 | PhosphoSitePlus | |||
S105 | Phosphorylation | score1 | PhosphoSitePlus | |||
K126 | Ubiquitination | score1 | PhosphoSitePlus | |||
S141 | Phosphorylation | score1 | PhosphoSitePlus | |||
S144 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K159 | Ubiquitination | score1 | PhosphoSitePlus | |||
K161 | Ubiquitination | score1 | PhosphoSitePlus | |||
S163 | O-Glycosylation | score1 | GlyGen | 32574038, 31492838, 29351928, ...34019948, 29485866, 31373491, 30059200 | ||
T164 | O-Glycosylation | score1 | GlyGen | 32574038, 31492838, 29351928, ...34019948, 29485866, 31373491, 30059200 | ||
S165 | O-Glycosylation | score1 | GlyGen | 32574038, 31492838, 29351928, ...34019948, 29485866, 31373491, 30059200 | ||
S167 | O-Glycosylation | score1 | GlyGen | 32574038, 31492838, 29351928, ...34019948, 29485866, 31373491, 30059200 | ||
K207 | Sumoylation | score1 | PhosphoSitePlus | |||
K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
S213 | Phosphorylation | score1 | PhosphoSitePlus | |||
S216 | Phosphorylation | score1 | PhosphoSitePlus | |||
T217 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
T236 | Phosphorylation | score1 | PhosphoSitePlus | |||
T243 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
G286 | Phosphorylation | score1 | UniProt | 19690332 | ||
S290 | Phosphorylation | score1 | PhosphoSitePlus | |||
S293 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K294 | Ubiquitination | score1 | PhosphoSitePlus | |||
S300 | Phosphorylation | score1 | PhosphoSitePlus | |||
K305 | Ubiquitination | score1 | PhosphoSitePlus | |||
K331 | Ubiquitination | score1 | PhosphoSitePlus | |||
T345 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y349 | Phosphorylation | score1 | PhosphoSitePlus | |||
S354 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 18318008, ...19367720, 18669648, 24275569, 19690332, 20068231 | ||
S376 | Phosphorylation | score1 | PhosphoSitePlus | |||
T459 | Phosphorylation | score1 | PhosphoSitePlus | |||
S460 | Phosphorylation | score1 | PhosphoSitePlus | |||
S463 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 20068231 |
Site | PTM Type | PTM Enzyme |
Score
| Source | PMID | |
---|---|---|---|---|---|---|
S144 | Phosphorylation | score0 | HPRD | 19413330, 20068231 | ||
T217 | Phosphorylation | score0 | HPRD | 17525332 | ||
T243 | Phosphorylation | score0 | HPRD | 20068231 | ||
S354 | Phosphorylation | score0 | HPRD | 17322306, 18491316, 18767875, ...19664994, 19007248, 18452278, 19651622, 18510355, 18669648, 20187088, 20166139, 19415658, 20068231 | ||
S463 | Phosphorylation | score0 | HPRD | 20068231 |
Site | PTM Type | PTM Enzyme |
Score
| Source | PMID | |
---|---|---|---|---|---|---|
S286 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S163 | I163 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S167 | C167 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
S167 | T167 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
K305 | N305 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S460 | F460 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S460 | C460 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S463 | Y463 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |