iPTMnet Report for Q96K21 (ZFYVE19)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96K21 / ANCHR_HUMAN
Protein Name Abscission/NoCut checkpoint regulator
Gene Name Name: ZFYVE19
Synonyms:ANCHR,MPFYVE;
Organism Homo sapiens (Human)

PRO ID PR:Q96K21
DAG View
PRO Name abscission/NoCut checkpoint regulator (human)
Definition An abscission/NoCut checkpoint regulator that is encoded in the genome of human.
Short Label hZFYVE19
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96K21 (ZFYVE19) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y3 Phosphorylation PhosphoSitePlus
S5 Phosphorylation PhosphoSitePlus
Y15 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus   UniProt 23186163
K159 Ubiquitination PhosphoSitePlus
K161 Ubiquitination PhosphoSitePlus
S163 O-Glycosylation GlyGen 32574038, 31492838, 29351928, ...34019948, 29485866, 31373491, 30059200
T164 O-Glycosylation GlyGen 32574038, 31492838, 29351928, ...34019948, 29485866, 31373491, 30059200
S165 O-Glycosylation GlyGen 32574038, 31492838, 29351928, ...34019948, 29485866, 31373491, 30059200
S167 O-Glycosylation GlyGen 32574038, 31492838, 29351928, ...34019948, 29485866, 31373491, 30059200
K207 Sumoylation PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
T217 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
T236 Phosphorylation PhosphoSitePlus
T243 Phosphorylation PhosphoSitePlus   UniProt 20068231
S278 Phosphorylation PhosphoSitePlus
G286 Phosphorylation UniProt 19690332
S290 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus   UniProt 23186163
K294 Ubiquitination PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
Y349 Phosphorylation PhosphoSitePlus
S354 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18318008, ...19367720, 18669648, 24275569, 19690332, 20068231
S376 Phosphorylation PhosphoSitePlus
T459 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
S463 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
Site PTM Type PTM Enzyme Score Source PMID
S144 Phosphorylation HPRD 19413330, 20068231
T217 Phosphorylation HPRD 17525332
T243 Phosphorylation HPRD 20068231
S354 Phosphorylation HPRD 17322306, 18491316, 18767875, ...19664994, 19007248, 18452278, 19651622, 18510355, 18669648, 20187088, 20166139, 19415658, 20068231
S463 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S286 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S163 I163 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S167 C167 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S167 T167 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K305 N305 Biomuta DOID:1324 / lung cancer [ cosmic ]
S460 F460 Biomuta DOID:363 / uterine cancer [ icgc ]
S460 C460 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S463 Y463 Biomuta DOID:3571 / liver cancer [ cosmic ]