iPTMnet Report for Q96JB3 (HIC2)
Protein Information
| UniProt AC / UniProt ID | Q96JB3 / HIC2_HUMAN |
| Protein Name | Hypermethylated in cancer 2 protein |
| Gene Name | Name: HIC2 Synonyms:HRG22,KIAA1020,ZBTB30; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96JB3 |
| PRO Name | hypermethylated in cancer 2 protein (human) |
| Definition | A hypermethylated in cancer 2 protein that is encoded in the genome of human. |
| Short Label | hHIC2 |
| Category | organism-gene |
DAG ViewQ96JB3 (HIC2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S153 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S166 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S169 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S197 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S253 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S280 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S348 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S412 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T612 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S613 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S197 | L197 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T612 | A612 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
| S613 | P613 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S613 | Y613 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
