iPTMnet Report for Q96HE7 (ERO1A)
Protein Information
| UniProt AC / UniProt ID | Q96HE7 / ERO1A_HUMAN |
| Protein Name | ERO1-like protein alpha precursor |
| Gene Name | Name: ERO1A Synonyms:ERO1L;ORFNames:UNQ434/PRO865; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96HE7 |
| PRO Name | ERO1-like protein alpha (human) |
| Definition | An ERO1-like protein alpha that is encoded in the genome of human. |
| Short Label | hERO1A |
| Category | organism-gene |
DAG ViewQ96HE7 (ERO1A) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K67 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S71 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y73 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R75 | Methylation | score1 | PhosphoSitePlus | |||
| S106 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| S121 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C131 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| S143 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 20068231 | ||
| S145 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 29858230 | ||
| K150 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K192 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y248 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y266 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N280 | N-Glycosylation | score2 | GlyGen UniProt | 23090970, 29741879, 19159218, ... | ||
| T282 | O-Glycosylation | score1 | GlyGen | 23301498, 34019948, 34725712, ... | ||
| T293 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S353 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K368 | Acetylation | score1 | PhosphoSitePlus | |||
| T405 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y431 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K67 | T67 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S71 | N71 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| C131 | Y131 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K192 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
| Y248 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| N280 | H280 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
| K368 | N368 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| Y431 | H431 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
