iPTMnet Report for Q96HE7 (ERO1A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96HE7 / ERO1A_HUMAN
Protein Name ERO1-like protein alpha precursor
Gene Name Name: ERO1A
Synonyms:ERO1L;ORFNames:UNQ434/PRO865;
Organism Homo sapiens (Human)

PRO ID PR:Q96HE7
DAG View
PRO Name ERO1-like protein alpha (human)
Definition An ERO1-like protein alpha that is encoded in the genome of human.
Short Label hERO1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96HE7 (ERO1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y59 Phosphorylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
R75 Methylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus   UniProt 24275569
S121 Phosphorylation PhosphoSitePlus
C131 S-Nitrosylation dbSNO 26338901
S143 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
S145 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 29858230
K150 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
Y248 Phosphorylation PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
N280 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
T282 O-Glycosylation GlyGen 23301498, 34019948, 34725712, ...26853435, 35254053
T293 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus
K368 Acetylation PhosphoSitePlus
T405 Phosphorylation PhosphoSitePlus
Y431 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K67 T67 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S71 N71 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
C131 Y131 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K192 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y248 * Biomuta DOID:4159 / skin cancer [ cosmic ]
N280 H280 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
K368 N368 Biomuta DOID:363 / uterine cancer [ icgc ]
Y431 H431 Biomuta DOID:4159 / skin cancer [ cosmic ]