iPTMnet Report for Q96CN7 (ISOC1)
Protein Information
UniProt AC / UniProt ID | Q96CN7 / ISOC1_HUMAN |
Protein Name | Isochorismatase domain-containing protein 1 |
Gene Name | Name: ISOC1 ORFNames:CGI-111; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q96CN7 |
PRO Name | isochorismatase domain-containing protein 1 (human) |
Definition | An isochorismatase domain-containing protein 1 that is encoded in the genome of human. |
Short Label | hISOC1 |
Category | organism-gene |
Q96CN7 (ISOC1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K131 | Acetylation | score1 | PhosphoSitePlus | |||
Y132 | Phosphorylation | score1 | PhosphoSitePlus | |||
T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y160 | Phosphorylation | score1 | PhosphoSitePlus | |||
K162 | Ubiquitination | score1 | PhosphoSitePlus | |||
R245 | Methylation | score1 | PhosphoSitePlus | |||
K279 | Acetylation | score1 | PhosphoSitePlus | |||
K279 | Ubiquitination | score1 | PhosphoSitePlus | |||
K286 | Acetylation | score1 | PhosphoSitePlus | |||
K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
S296 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K131 | R131 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K162 | Q162 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K162 | E162 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S296 | P296 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |