iPTMnet Report for Q96CN7 (ISOC1)
Protein Information
| UniProt AC / UniProt ID | Q96CN7 / ISOC1_HUMAN |
| Protein Name | Isochorismatase domain-containing protein 1 |
| Gene Name | Name: ISOC1 ORFNames:CGI-111; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q96CN7 |
| PRO Name | isochorismatase domain-containing protein 1 (human) |
| Definition | An isochorismatase domain-containing protein 1 that is encoded in the genome of human. |
| Short Label | hISOC1 |
| Category | organism-gene |
Q96CN7 (ISOC1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K131 | Acetylation | score1 | PhosphoSitePlus | |||
| Y132 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y160 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K162 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R245 | Methylation | score1 | PhosphoSitePlus | |||
| K279 | Acetylation | score1 | PhosphoSitePlus | |||
| K279 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K286 | Acetylation | score1 | PhosphoSitePlus | |||
| K286 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S296 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K131 | R131 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K162 | Q162 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K162 | E162 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S296 | P296 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |
DAG View