iPTMnet Report for Q96CN7 (ISOC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q96CN7 / ISOC1_HUMAN
Protein Name Isochorismatase domain-containing protein 1
Gene Name Name: ISOC1
ORFNames:CGI-111;
Organism Homo sapiens (Human)

PRO ID PR:Q96CN7
DAG View
PRO Name isochorismatase domain-containing protein 1 (human)
Definition An isochorismatase domain-containing protein 1 that is encoded in the genome of human.
Short Label hISOC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q96CN7 (ISOC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K131 Acetylation PhosphoSitePlus
Y132 Phosphorylation PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
Y160 Phosphorylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
R245 Methylation PhosphoSitePlus
K279 Acetylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K286 Acetylation PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K131 R131 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K162 Q162 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K162 E162 Biomuta DOID:3571 / liver cancer [ cosmic ]
S296 P296 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]